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2022 NFL Week 12 Fantasy Waiver Wire Picks

By Jeff Stinger

The fantasy football playoffs are just around the corner and most leagues are also past their trade deadlines as well. This makes waiver wire moves all the more crucial heading into the final stretch. Thankfully, we have just the thing to upgrade your fantasy roster for a strong postseason run with our latest picks for the best free agents in fantasy football and, in this week’s case, an actual free agent in the NFL with a ton of upside.

Nitrobetting is ready to equip its bettors with the latest news, NFL odds, and special features for the entire duration of the 2022 NFL season. This time, let’s take a closer look at the hottest waiver wire targets in fantasy football heading into Week 12.

Top Fantasy Football Waiver Wire Targets in 2022 NFL Week 12

READ MORE: 2022 NFL Week 12 Odds, Overview & Picks


Taylor Heinicke – Commanders

  • Pct. Owned: 23.7%

Hot off a huge upset over the Eagles, Washington backup quarterback Taylor Heinicke continued his streak of sound performances under center in Week 11 with a road win over the Texans.

Although Heinicke failed to throw a passing touchdown and finished this past Sunday’s game with only 191 passing yards, he snapped his streak of four straight games with an interception. He’ll have a shot at putting up decent fantasy numbers in Week 12 as a streaming option when the Commanders host the Falcons as (-4.5) home favorites. Atlanta has allowed the ninth-most fantasy points to opposing QBs and was just recently torched by Chicago’s Justin Fields.

Running Back

James Cook – Bills

  • Pct. Owned: 20.8%/li>

Buffalo’s offense remained explosive this past week and the team utilized the running game to huge success for a change. In turn, rookie running back James Cook broke out for 86 rushing yards against the Browns and tied for the team lead in that department with running mate Devin Singletary. However, Cook needed only 11 carries to hit that mark as opposed to 18 touches from Singletary.

For as long as the Bills get their backfield duo more involved outside of passing situations, Cook is a valued fantasy handcuff for Singletary owners and a sleeper flex start moving forward in deeper leagues. The former Georgia standout will have a great opportunity to boost his fantasy value when the Bills enter the Motor City as (-9) road favorites to beat the Lions on Thanksgiving.

Samaje Perine – Bengals

  • Pct. Owned: 3.8%

Another handcuff worth a second look is Cincinnati’s Samaje Perine, who caught four passes from Joe Burrow in Week 11 for 52 receiving yards and with three of those four catches resulting in trips to the end zone.

With Joe Mixon getting more attention from Pittsburgh’s front seven this past week considering his five-TD explosion in Week 10, the Bengals utilized their pass-catching back to the fullest instead. Perine is a solid fantasy pickup even for non-Mixon owners, albeit only in PPR leagues as his rushing stats aren’t very appealing in standard-scoring formats.

Wide Receiver

Odell Beckham Jr. – Free Agent

  • Pct. Owned: 29.9%

It’s only a matter of time before Odell Beckham Jr. returns to the field and fantasy managers are still holding on to the hope that the phenomenal wideout will play this season. Nearly 30 percent of fantasy leagues, to be exact.

Whichever team acquires Beckham for a late-season push will immediately get a boost on offense, and so too will OBJ owners who took a gamble on stashing the three-time Pro Bowl selection. He’s still available in a majority of fantasy leagues, though, so perhaps now is the best time to take a flyer on the highlight reel machine before his ownership skyrockets on the exact day of signing with his new team.

Treylon Burks – Titans

  • Pct. Owned: 22.7%

There’s no denying that the Titans’ offense runs way better with Ryan Tannehill under center. In last week’s Thursday night clash win against the Packers, Tannehill threw for 333 passing yards and a pair of passing TDs and there was no bigger benefactor than rookie wide receiver Treylon Burks.

Burks led his team that day with eight targets, seven catches, and 111 receiving yards for his first 100-yard receiving game in the NFL. The 18th-overall pick out of Arkansas was drafted by Tennessee as the replacement for A.J. Brown and he’s finally broken through with his best performance in the big leagues. Expect Burks’ fantasy value to rise even higher this week when the Titans take on a Bengals defense that just gave up 30 points to a relatively putrid Pittsburgh offense.

Tight End

Juwan Johnson – Saints

  • Pct. Owned: 12.3%

It’s tempting to put another Tennessee player in this slot after Austin Hooper hauled two TD catches (one from Derrick Henry!). However, Juwan Johnson is quietly doing the fantasy gods’ work in the Big Easy on a more consistent basis.

Johnson caught his fifth receiving touchdown of the season in his last five starts and has put up at least 40 receiving yards in each of the last three games. The 26-year-old undrafted prospect is one of the few bright spots in an otherwise middling New Orleans offense. More fantasy managers will be giving Johnson a spot on their rosters this week after proving that his value as an end-zone threat is real, especially with the likes of the Saints’ top weapons in Alvin Kamara and Jarvis Landry continuing to underwhelm with Andy Dalton at the helm of the offense.

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*All stated odds are subject to change without prior notice.

READ MORE: 2022 NFL Week 13 Fantasy Waiver Wire Picks