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2023 NFL Week 12 Odds, Overview & Picks

By Hank Blaine

NFL Thanksgiving Thursday happens on November 23. Then on Black Friday, the NFL has a game for the first time when the Dolphins head to MetLife Stadium to take on the Jets. Sunday provides a decent amount of NFL action before the Monday Night Football showdown between the Chicago Bears and the Minnesota Vikings. See below for NFL odds, analysis, and free picks for every game on the NFL Week 12 schedule.

Top 2023 NFL Week 12 Games to Bet

READ MORE: 2023 NFL Week 12 Sleeper Picks

Green Bay Packers vs. Detroit Lions

Jordan Love played great in Green Bay’s last, a 23-20 victory over the Chargers. But the Bolts don’t have a good defense. In fact, it’s downright bad.

Detroit is one of the NFL’s top teams this season. The Lions are good enough to win the Super Bowl and dusted the Packers in the first meeting earlier in 2023. Detroit dominates.

2023 NFL Week 12 Pick: Detroit Lions

Washington Commanders vs. Dallas Cowboys

After watching how the Commanders helped Giants quarterback Tommy DeVito look like Phil Simms, it’s tough to back D.C. against anybody. Sure, the Dallas Cowboys are a rival squad.

And, yes, 10.5 points is a lot, but Washington lost 31-17 to NYG at home this past Sunday. Big D has no problems covering the spread.

2023 NFL Week 12 Pick: Dallas Cowboys

San Francisco 49ers vs. Seattle Seahawks

The 49ers head to Seattle on a roll. San Francisco followed up an impressive 34-3 road win against the Jaguars in week 10 with a 27-14 win versus the Tampa Bay Buccaneers.

But although San Francisco has won back-to-back, the 49ers are just 1-3 against the spread in their last 4. Ah, but the last non-cover victory against the Bucs came by half a point. SF knows what’s at stake on Thursday night. 49ers roll.

2023 NFL Week 12 Pick: San Francisco 49ers

Miami Dolphins vs. New York Jets

Robert Saleh bench quarterback Zach Wilson and will go with Tim Boyle on Friday night. Boyle should have a minimal impact. The Jets’ defense is good but it allows way too many rushing yards and Mike McDaniel likes to rush the ball as much as he likes to pass. The Fins get it done.

2023 NFL Week 12 Pick: Miami Dolphins

New Orleans Saints vs. Atlanta Falcons

Atlanta will go back to Desmond Ridder for their key game against the rival New Orleans Saints. Ridder plays well at home.

But on Sunday, Ridder faces one of the better defensive teams in the NFL. Not only that, but in recent matchups, the Saints have had Atlanta’s number in road contests. New Orleans takes a 2-game division lead over their top rivals.

2023 NFL Week 12 Pick: New Orleans Saints

Pittsburgh Steelers vs. Cincinnati Bengals

Pittsburgh HC Mike Tomlin fired offensive coordinator Matt Canada earlier this week. Letting Canada go should rally the Steelers offense.

New play-caller Mike Sullivan will allow Kenny Pickett to do what every college football fan knows he can do, throw the football long. Expect the Steelers offense to really step it up versus a Bengals’ squad that must play without Joe Burrow for the rest of the season.

2023 NFL Week 12 Pick: Pittsburgh Steelers

Jacksonville Jaguars vs. Houston Texans

As long as C.J. Stroud is healthy, the Texans can beat any team. Stroud is that kind of NFL quarterback, the kind that always keeps his team in the game.

The line, though, makes the Jags an overlay. Jacksonville flubbed against the 49ers. The Jags reaction in their next game, blasting the Titans 34-14, is a testament to Jacksonville’s quality.

2023 NFL Week 12 Pick: Jacksonville Jaguars

Tampa Bay Buccaneers vs. Indianapolis Colts

Since starting the season 2-1 straight up, Tampa has since gone 1-5 in their last 6 games. The only win was a victory over the Titans at home. So, no, the Bucs won’t hang with the Colts.

2023 NFL Week 12 Pick: Indianapolis Colts

New England Patriots vs. New York Giants

The Giants blasted the Commanders on the road in their last. By blast, we mean the Giants dominated D.C.

New England heads to MetLife after a bye, but the Patriots aren’t a good team. Also NYG always seems to play the Patriots tough. Giants should win this straight up.

2023 NFL Week 12 Pick: New York Giants

Carolina Panthers vs. Tennessee Titans

If Carolina is smart, they will bench Bryce Young for the rest of the season. Young is getting worse because a) he plays behind a dreadful offensive line and b) he has no skill players he can lean on except Adam Thielen.

There’s also the chance Young suffers an injury from which he can’t recover. When it comes to this game, whether Young plays or not, it doesn’t matter. The Titans win and cover.

2023 NFL Week 12 Pick: Tennessee Titans

L.A. Rams vs. Arizona Cardinals

It’s tough to go with either squad in this matchup. The Cardinals are at home and Kyler Murray will play. So Zona has a shot.

The Rams are almost one-hundred percent healthy. Since LAR beat Seattle in their last, they should have no issue getting by the Cards. That’s the logic we’re going with.

2023 NFL Week 12 Pick: L.A. Rams

Cleveland Browns vs. Denver Broncos

Dorian Thompson-Robinson was the winning quarterback for the Browns in their shocking defeat of the Pittsburgh Steelers last Sunday. However, DTR didn’t play well.

This Sunday, DTR and the Browns take on the streaking Denver Broncos. The Colorado Ponies will be looking for their fifth straight win. Amazingly, the Broncos are just 2 games behind the Kansas City Chiefs in the AFC West. So Sean Payton and Russell Wilson really want this win.

2023 NFL Week 12 Pick: Denver Broncos

Kansas City Chiefs vs. Las Vegas Raiders

The Chiefs have lost 2-of-3. As odd is the fact the KC offense has scored 9, 21, and 17 points in KC’s last 3 games.

The Raiders played well in defeat versus the Miami Dolphins last Sunday. This is a massive rivalry game and Vegas is playing great. Don’t be surprised when Aidan O’Connell leads to a straight up victory over the Chiefs.

2023 NFL Week 12 Pick: Las Vegas Raiders

Buffalo Bills vs. Philadelphia Eagles

Philadelphia went into KC and proved they could win a game with their defense. On Sunday, the Eagles paste the Bills as a -3.5 home chalk.

Josh Allen doesn’t play great on the road. Buffalo’s defense will struggle to contain Jalen Hurts and the Eagles offense. A 10-point Eagles win is possible.

2023 NFL Week 12 Pick: Philadelphia Eagles

Baltimore Ravens vs. L.A. Chargers

Baltimore should dominate the Chargers. Simply put, Baltimore is one of the beset teams in the NFL while the Bolts’ high-cost defense can’t stop anybody. Lamar runs and throws at will.

2023 NFL Week 12 Pick: Baltimore Ravens

Chicago Bears vs. Minnesota Vikings

Chicago is a much better team with Justin Fields at quarterback. The Bears almost pulled off an upset road win against the Detroit Lions in their last.

Minnesota is playing decent defense and Joshua Dobbs isn’t a drop off from Kirk Cousins. So although Chicago will play well in this, the Vikings get the nod to win and cover.

2023 NFL Week 12 Pick: Minnesota Vikings

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READ MORE: 2023 Nitro NFL Survivor Pools Week 11 Recap

*All stated odds are subject to change without prior notice.